Our Story
Your skin. Our science. Pure chemistry. A quarter century of clinically validated skincare, built on evidence and the belief that great skincare can transform lives.
Explore the JourneyGuided by science since 2000
Co-founders Bryan Johns and Alec Call set out to elevate the physical and emotional well-being of people worldwide. From humble beginnings to a globally recognised skincare authority, iS Clinical is guided by integrity, positivity and innovation, and the belief that great skincare can transform lives.
Helping people be their best
As an innovation-driven skincare brand, we create clinically validated products that enhance well-being worldwide. Our mission is to help people embrace their best selves through care, integrity and innovation, making a positive impact on both people and the planet.
Four steps. Proven results.
Potent, multitasking formulations deliver visible, clinically proven results for all skin types, genders and ages. Our four-step system improves skin health, with formulations free from parabens, phthalates and sulphates, and never tested on animals.
Cleanse
Treat
Hydrate
Protect
Breakthroughs, clinically proven
Innovation defines iS Clinical. From our award-winning Active Serum to proprietary Extremozyme® and GeneXC® technologies, we create skincare breakthroughs backed by independent, peer-reviewed clinical studies and trusted by professionals worldwide.
A better future, worldwide
Guided by the principle of doing the right thing the right way, iS Clinical is dedicated to sustainability at every level. From responsibly sourced ingredients and recyclable packaging to energy-efficient operations and reduced carbon footprint initiatives, we are committed to creating a better, more sustainable future.
The iS Clinical Journey
Twenty-five years of clinical firsts, proprietary technologies and milestones that shaped professional skincare. Select a year to explore.
A brand built on science
Bryan Johns and Alec Call found iS Clinical under Innovative Skincare, with a mission to elevate the physical and emotional well-being of people worldwide.
Active Serum and Cleansing Complex launch
Active Serum becomes an instant bestseller, addressing everything from blemishes to uneven tone. Cleansing Complex follows as a repeat award winner and our number one product.
Giving back becomes part of who we are
The iS Cancer Care programme begins with its first Spa Day initiative, alongside quarterly education classes for skincare professionals.
The Fire & Ice Facial debuts
A red-carpet must-have, this warming and cooling professional treatment revitalises and invigorates the skin.
Pro-Heal Serum Advance+ launches
A first-of-its-kind Vitamin C serum, optimised to calm redness and soothe sensitive skin.
Extremozyme® Technology unveiled
A proprietary combination of extremophilic enzymes, clinically proven to protect skin from environmental stressors.
GeneXC® Technology introduced
An exclusive breakthrough powered by Extremozymes and Vitamin C that protects skin while visibly enhancing firmness and elasticity.
Active Peel System arrives
Our transformative at-home treatment launches and wins Allure Best of Beauty, with further recognition from Health and Marie Claire.
More than 125 countries
iS Clinical expands its professional skincare to more than 125 countries around the world.
Extra Strength Active Peel Brightening System
Available exclusively through iS Clinical professionals, this system offers three times the brightening and exfoliating power.
Find the routine made for your skin
Take our clinically developed Skin Quiz to build a targeted four-step system, matched to your skin type and concerns.